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KMID : 0352120150300010001
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Journal of Kyung Hee University
2015 Volume.30 No. 1 p.1 ~ p.8
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Diagnosis and Treatment of Age-related Malcuar Degeneration
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Yu Seung-Young
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Abstract
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Age-related macular degeneration (AMD) is a deterioration of the central portion of the retina which facilitate central vision and permit high-resolution visual acuity. AMD is the third cause of irreversible severe visual loss in the gobal people and the prevalence of AMD has increased in Korea, according to increase a population of older age. AMD can be classified into early and late stages. The early stage is associated with minimal visual impairment and is characterized by large drusen and pigmentary abnormalities in the macula. There are two forms of late age-related macular degeneration: the atrophic form and the neovascular, exudative form. Accurate diagnosis combines clinical examination and investigations, including retinal photography, angiography, and optical coherence tomography. There is currently no completely cure for macular degeneration, but treatments may prevent severe vision loss or slow the progression of the disease considerably. Recently, intravitreal treatment with humanised monoclonal antibodies against vascular endothelial growth factor is used to ameliorate the acute manifestations of neovascular age related macular degeneration. In its earliest stages, people may not be aware they have macular degeneration until they notice slight changes in their vision or until it is detected during an eye exam. While there is little that can be done to improve the eyesight of someone who has AMD, with early detection, the rate of vision loss can be slowed. The important things to provide against AMD are to understand macular degeneration, monitor the symptoms and visit hospital regularly to test the vision.
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KEYWORD
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Age-related macular degeneration, Drusen, Neovascular age related macular degeneration, Fluorescein angiography, Antivascular endothelial growth factor
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